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Arcturus Therapeutics Holdings Inc是一家晚期全球臨床信使核糖核酸(mRNA)藥物公司。該公司專注於傳染病疫苗的開發以及肝臟和呼吸道罕見疾病領域的重大機遇。除了其mRNA平台,該公司的脂質納米粒(LNP)輸送系統LUNAR還有潛力實現多種核酸藥物,其自擴增mRNA技術(自轉錄和復制RNA(STARR)技術)有潛力在較低劑量水平下提供更持久的RNA和持續的蛋白質表達。該公司使用STARR技術開發的產品有ARCT-021、ARCT-154和ARCT-165。其COVID-19候選疫苗ARCT-021基於其STARR技術平台,正在進行II期臨床試驗。其LUNAR-FLU疫苗由Liver Franchise ARCT-810 (LUNAR-OTC)和Lung Franchise ARCT-032 (LUNAR-CF)組成。
名稱 | 年齡 | 成立於 | 主旨 |
---|---|---|---|
Andrew H. Sassine | 57 | 2018 | CFO & Director |
Peter C. Farrell | 79 | 2018 | Independent Chairman of the Board |
Karah Herdman Parschauer | 43 | 2019 | Director |
Joseph E. Payne | 49 | 2013 | Founder, President, CEO & Director |
Peter A. Patriarca | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Robert T. Schooley | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Eng Eong Ooi | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jeffrey William Colyer | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Frederick G. Hayden | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jonathan F. Smith | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jing L. Marantz | 57 | 2021 | Independent Director |
Magda Marquet | 64 | 2018 | Independent Director |
Michael R. Hodges | - | 2014 | Member of Scientific Advisory Board |
Drew Weissman | - | 2015 | Member of Scientific Advisory Board |
James F. Barlow | 64 | 2018 | Independent Director |
Steven George Hughes | 55 | 2022 | Strategic Clinical Advisor & Member of Scientific Advisory Board |
Edward W. Holmes | 82 | 2019 | Independent Director |
John H. Markels | 58 | 2022 | Independent Director |
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