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Apellis Pharmaceuticals Inc是一家商業階段的生物製藥公司。該公司專注於開發通過抑制補體系統來治療疾病的治療化合物。該公司正在與Sobi開髮用於全身給藥的pegcetacoplan用於多種適應症,包括陣發性夜間血紅蛋白尿、C3腎小球病、免疫複合物膜增殖性腎小球腎炎、肌萎縮側索硬化症、冷凝集素病和造血幹細胞移植血栓性微血管病。該公司針對第3成分的先進臨床計劃,對其主要候選產品pegcetacoplan進行了III期臨床試驗,用於多種適應症。Pegcetacoplan是一種康普他汀類似物的結合物,既可通過直接注射到眼睛中進行眼科給藥,也可通過皮下注射(即註射到皮下組織中)進行全身給藥。
名稱 | 年齡 | 成立於 | 主旨 |
---|---|---|---|
Lokchung Chan | 70 | 2013 | Independent Chairman of the Board |
Cedric Francois | 49 | 2009 | Co-Founder, President, CEO & Director |
Stephanie Monaghan O’Brien | 64 | 2013 | Independent Director |
Jason Scott Slakter | 65 | 2015 | Member of AMD Scientific Advisory Board |
Gabriel J. Coscas | - | 2015 | Member of AMD Scientific Advisory Board |
Marsha Wills-Karp | - | - | Member of Pulmonology Scientific Advisory Board |
Paul R. Fonteyne | 62 | 2020 | Independent Director |
A. Sinclair Dunlop | 51 | 2010 | Independent Director |
Dave Singh | - | 2015 | Member of Pulmonology Scientific Advisory Board |
Claudia Kemper | - | 2015 | Member of Pulmonology, AMD & PNH Scientific Advisory Board |
Robert A. Brodsky | - | 2015 | Member of PNH Scientific Advisory Board |
Johanna M. Seddon | - | 2015 | Member of AMD Scientific Advisory Board |
Susan M. Lea | - | 2015 | Member of Pulmonology, AMD & PNH Scientific Advisory Board |
Philip J. Rosenfeld | - | 2015 | Member of AMD Scientific Advisory Board |
Bruno Crestani | - | 2015 | Member of Pulmonology Scientific Advisory Board |
Toby Maher | - | 2015 | Member of Pulmonology Scientific Advisory Board |
Janet Stoltz Sunness | - | 2015 | Member of AMD Scientific Advisory Board |
Michael Yeadon | - | 2015 | Member of Pulmonology Scientific Advisory Board |
Carl Atkinson | - | 2015 | Member of Pulmonology Scientific Advisory Board |
Jaroslaw Maciejewski | - | 2015 | Member of PNH Scientific Advisory Board |
Alec Machiels | 51 | 2009 | Co-Founder & Director |
Peter Hillmen | - | 2015 | Head of Hematology Engagement & Member of PNH Scientific Advisory Board |
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